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Year 2007 - Volume 27, Number 06
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Características morfométricas do desenvolvimento do timo em cães, p.236-240
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ABSTRACT.- Agreste F.R., Bombonato P.P. & Hernandez-Blazquez, F.J. 2007. [Morphometric characteristics of thymus development in dogs.] Características morfométricas do desenvolvimento do timo em cães. Pesquisa Veterinária Brasileira 27(6):236-240. Departamento de Cirurgia, Setor de Anatomia dos Animais Domésticos e Silvestres, Universidade de São Paulo, Avenida Prof. Dr. Orlando Marques de Paiva 87, São Paulo, SP 05508-000, Brazil. E-mail: bombonat@usp.br
The thymus is an organ with great immunological relevance during foetus life and neonatal period, It is the predecessor of lymphopoiesis and shows high lymphopoietic activity, being also the largest lymphoid organ during intrauterine life and at birth. In this study, the morphological aspects of the prenatal development of dog thymus were described in foetus of different ages and sexes. Twenty-four foetus of mongrel domestic dogs, males and females, were divided into four age groups. The thymus presented two lobes linked by a rose-colored tissue connection that was localized in the cranial mediastinal space. The cranial portion protrudes slightly beyond the first pair of ribs. The cells that formed the thymus parenchyma were well organized. Concentric aggregates named Hassal corpuscles were observed, involved by a thin capsule of connective tissue thickened by adipose tissue. The vessels size gradually increased with the foetus age, being larger in animals that were closer to birth. The volume (Vref) and size parameters of female thymus were larger than in males. |
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