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Year 2018 - Volume 38, Number 12
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Malformation of the tail in Labrador Retriever dogs caused by mutation C189G in the T gene, 38(12):2237-2240
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ABSTRACT.- Silva D.M., Miguel G.G.P., Souza M.L., Cleveland H.P.K. & Ramos C.A.N. 2018. Malformation of the tail in Labrador Retriever dogs caused by mutation C189G in the T gene. Pesquisa Veterinária Brasileira 38(12):2237-2240. Faculdade de Medicina Veterinária e Zootecnia, Universidade Federal de Mato Grosso do Sul, Av. Senador Filinto Muller 2443, Vila Ipiranga, Campo Grande, MS 79070-900, Brazil. E-mail: carlos.nascimento@ufms.br
The present study reported the mutation C189G in the T gene (Brachyury gene) as the cause of malformation in the tail of the Labrador dog. One litter of Labradors, from a mating between a female with short tail and a male with normal tail admitted at the Veterinary Teaching Hospital of Universidade Federal de Mato Grosso do Sul, Campo Grande, Brazil, was evaluated in this study. Blood samples were collected from the female and her puppies. After DNA extraction, sequencing and PCR-RFLP were carried out. The C189G mutation was identified through both techniques only in dogs with short tail. |
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