 |
|
|
|
Year 2018 - Volume 38, Number 12
|
.jpg)
|
Ceftaroline resistance in Staphylococcus pseudintermedius gene mecA carriers, 38(12):2233-2236
|
ABSTRACT.- Scherer C.B., Botoni L.S., Carvalho A.U., Keller K.M. & Costa-Val A.P. 2018. Ceftaroline resistance in Staphylococcus pseudintermedius gene mecA carriers. Pesquisa Veterinária Brasileira 38(12):2233-2236. Departamento de Clínica e Cirurgia, Escola de Medicina Veterinária, Universidade Federal de Minas Gerais, Av. Antônio Carlos 6627, Cx. Postal 567, Belo Horizonte, MG 31270-901, Brazil. E-mail: adriane@ufmg.br
Infections caused by methicillin-resistant Staphylococcus aureus (MRSA) being a constant concern, ceftaroline fosamil has been recently approved as a new cephalosporin, active against MRSA, for use in humans; only rare cases of resistance have been reported till date. There is no report of resistance to ceftaroline in Staphylococcus pseudintermedius, which is the main bacterium causing dermatitis and otitis in dogs. To evaluate staphylococcal resistance to ceftaroline, 35 isolates of methicillin-resistant S. pseudintermedius (MRSP), carrying the mecA gene, from 26 dogs with folliculitis and nine dogs with external otitis, underwent disk diffusion test with cefoxitin, oxacillin, and ceftaroline. Tests with cefoxitin and oxacillin showed > 90% sensitivity in methicillin resistance detection. In the disk diffusion test, 97.14% (34/35) were resistant to cefoxitin, 94.29% (33/35) to oxacillin, and 31.43% (11/35) to ceftaroline. Of the ceftaroline-resistant strains, 27.27% (3/11) were obtained from the ears of dogs while the rest (8/11) were from the skin. The current report is the first description of MRSP resistance to ceftaroline. |
| |
|
|
| |
|
|
