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Year 2018 - Volume 38, Number 11
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Nephroblastoma in a black-tufted marmoset (Callithrix penicillata), 38(11):2155-2158
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ABSTRACT.- Ferreira Junior J.A., Rissi D.R., Elias M.A., Leonardo A.S., Nascimento K.A., Macêdo J.T.S.A. & Pedroso P.M.O. 2018. Nephroblastoma in a black-tufted marmoset (Callithrix penicillata). [Nefroblastoma em um sagui-de-tufos-pretos (Callithrix penicillata).] Pesquisa Veterinária Brasileira 38(11):2155-2158. Laboratório de Patologia Veterinária, Hospital Veterinário, Fundação Universidade de Brasília, Via L4 Norte, Brasília, DF 70910-970, Brazil. E-mail: pedrosovet@yahoo.com.br
A renal nephroblastoma is described in a free-living black-tufted marmoset (Callithrix penicillata) in Central Brazil. The monkey was found dead and subjected to necropsy. Gross anatomic changes consisted of a ruptured left kidney, which was almost completely effaced by a white to yellow, partially encapsulated friable mass. The left ureter was distended due to obstruction by a red, spherical, 2mm in diameter friable mass. The urinary bladder was also distended. Histologically the renal and ureteral masses consisted of a triphasic embryonal neoplasm composed of embryonic epithelium forming glomeruli and tubules, polygonal blastemal cells, and a mesenchymal stroma. The embryonic epithelium exhibited rare nuclear immunoreactivity for WT-1, whereas blastemal cells exhibited robust cytoplasmic and rare nuclear immunoreactivity for WT-1; blastemal cells were also immunoreactive for vimentin. No immunoreactivity was detected for pan-cytokeratin (AE1/AE3), actin, and desmin. Morphological and immunohistochemical features of the present neoplasm are consistent with those described for renal nephroblastoma. |
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