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Year 2018 - Volume 38, Number 4
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Axillary lymph node as sentinel for mammary neoplasia in bitches, 38(4):692-695
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ABSTRACT.- Bianchi S.P., Gomes C., Pavarini S.P., Mombach V.S., Santos F.R., Vieira L.C., Oliveira L.O. & Contesini E.A. 2018. [Axillary lymph node as sentinel for mammary neoplasia in bitches.] Linfonodo axilar como sentinela de neoplasia mamária em cadelas. Pesquisa Veterinária Brasileira 38(4):692-695. Faculdade de Veterinária, Universidade Federal do Rio Grande do Sul, Avenida Bento Gonçalves 9090, Bairro Agronomia, Porto Alegre, RS 90540-000, Brazil. E-mail: simonepbianchi@gmail.com
Mammary tumors research in bitches is important due to their high incidence. The aim of this study was to evaluate the importance of the axillary lymph node as a sentinel lymph node for mammary neoplasms in female dogs. Forty-nine bitches with mammary neoplasia were submitted to total unilateral mastectomy, and the axillary lymph node was identified using the patent blue dye. This lymph node was processed routinely for histopathological analysis and stained with hematoxylin-eosin and by immunohistochemistry (IHC) with cytokeratin antibody (AE1/AE3) to search for metastasis. Eight dogs had axillary lymph node metastases, seven of which were detected by histopathology and by IHC and only one by IHC (micrometastasis). One dog who presented tumor in caudal and inguinal abdominal mammary glands had metastases in the axillary and inguinal lymph nodes. It is concluded that the mammary tumor can cause alteration in lymphatic drainage leading to metastases in lymph nodes which normally do not drain certain glands; so the removal of the axillary lymph node should be included as a routine technique to allow better staging of mammary neoplasms of bitches. |
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